My Father's best Friend (H Uncle) lives up in Scotland, the two of them have been friends since they were roommates in University over 40 years ago. I think its amazing that after 40 year they are just as close now as they were then, even if everything in their lives has changed. Its not just the two of them, both our families are close as you can be even if we can only see each other once or twice a year. Unfortunately a few years ago H Uncle started to suffer from Dementia and there is nothing anyone can do. The few times I've seen him since his illness were heartbreaking, especially cos of the effect its having on his family, to my dad it is like losing a brother all over again.
My best friend K and I have known each other for almost 8 years now, 5 of which we lived together as college roommates and then flat mates. In June she moved back home and even though I see her as often as we can, I still miss her. The girl is completely insane and makes no sense half the time (she'd probably say the same thing about me) and we are total opposites on about a thousand things. I'd rather read Milton while she'd rather do simultaneous equations. I've no doubt in 40 years time we'll be the same as we are now gossiping about one thing or another and giggling about things only the two of us remember.
The funny part was when we first moved into together I think both of us were sat there in our new room hoping the other wasn't going to turn out to be a psychopath.